Preclinical evaluation of dose-dependent effects of photobiomodulation therapy on persistent inflammation in the temporomandibular joint
This study highlights the dose-dependent efficacy of LLLT, with an intermediate dose (5 J/cm<sup>2</sup>) producing the most pronounced analgesic effects and the 5 and 10 J/cm<sup>2</sup> doses demonstrating significant therapeutic benefits in reducing acute and persistent TMJ inflammation. Importantly, even the lowest dose effectively modulated key components of the innate immune response, indicating its potential to reduce early inflammatory processes.
Authors
- Laís Valencise Magri (ORCID: https://orcid.org/0000-0001-8050-4396)
- Amanda de Carvalho Desiderá
- Vinícius Almeida Carvalho (ORCID: https://orcid.org/0000-0002-5393-227X)
- Christie Ramos Andrade Leite‐Panissi (ORCID: https://orcid.org/0000-0003-1762-2730)
- Antônio Roberto Martins (ORCID: https://orcid.org/0000-0002-9560-280X)
- Glauce Crivelaro Nascimento
Institutions
- Universidade de Ribeirão Preto (BR)
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Journal of Oral & Facial Pain and Headache
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22514/jofph.2025.037
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00