Effect of Non-pharmacological Interventions on Level of Symptoms Progression Among Patients with Carpal Tunnel Syndrome

Background: Carpal Tunnel Syndrome (CTS) is a common peripheral neuropathy characterized by pain, numbness, and functional limitations. Non-pharmacological treatments are often recommended as first-line interventions. Aim: This study aimed to evaluate the effect of non-pharmacological interventions on level of symptoms progression among patients with Carpal Tunnel Syndrome. Methods: Design: A quasi-experimental design was employed. Sample: The study included 120 patients diagnosed with mild to moderate CTS. Participants underwent non-pharmacological interventions including wrist splinting, nerve gliding exercises, and ergonomic modifications. Setting: Data was collected at neuro-surgery outpatient clinics affiliated with university hospitals. Tools for Data Collection: Assessment tools included demographic and job-related questionnaires, the Boston Carpal Tunnel Questionnaire (BCTQ), the Katz Hand Diagram (KHD), and grip strength measurements. Evaluations were conducted at three time-points: baseline, 6 weeks, and 12 weeks. Results: The sample was predominantly female and right-hand dominant, with a majority classified as moderately overweight and employed in occupations requiring repetitive wrist movements. Statistically significant improvements were observed overtime in BCTQ scores, grip strengths, and KHD patterns. Patients with mild CTS demonstrated greater improvement compared to those with moderate CTS. Conclusion: Early implementation of non-pharmacological interventions effectively reduces symptoms, enhances hand function, and slows disease progression in patients with CTS. Recommendations: Routine early screening and integration of non-pharmacological treatments should be prioritized, especially in occupational settings with a high risk for CTS. These low-risk interventions can be feasibly incorporated into workplace health programs to prevent disease progression and enhance quality of life.