High-dose amoxicillin and pantoprazole regimen for Helicobacter pylori eradication: a multi-center, multinational randomized controlled trial
The results of the current study show that for treating HP infection, high-dose amoxicillin-PPI dual therapy failed to achieve high eradication rates compared with a clarithromycin-based quadruple regimen. Clarithromycin-based quadruple therapy for <i>H. pylori</i> eradication has a higher eradication rate despite more side effects, and similar compliance compared to high-dose dual therapy.
Authors
- Siamak Baghaei
- Quang Trung Tran (ORCID: https://orcid.org/0000-0001-8347-1614)
- Azam Satari
- Mohammed Hussien Ahmed (ORCID: https://orcid.org/0000-0003-1761-3527)
- Mohammad Rezaei (ORCID: https://orcid.org/0000-0001-8508-1468)
- Ahmad Hormati (ORCID: https://orcid.org/0000-0002-1322-1318)
- Morteza Nayebi (ORCID: https://orcid.org/0000-0002-3815-9266)
- Omid Eslami (ORCID: https://orcid.org/0000-0003-0272-3416)
- Eskandar Hajiani (ORCID: https://orcid.org/0000-0002-1014-1996)
- Pezhman Alavinejad (ORCID: https://orcid.org/0000-0001-6857-6151)
- Abazar Parsi
- Shamaneh Mohamadi
Institutions
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Kerman University of Medical Sciences (IR)
- Hue University (VN)
- Shariati Hospital (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Gastroenterology Review
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5114/pg.2025.151887
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00