DRESS Syndrome in Patients With Drug-Induced Liver Injury: Characteristics and HLA Risk Factors
Patients with DILI and DRESS are younger, are more likely to be Black, have shorter time to DILI onset with more severe liver injury and higher overall and liver-related mortality. HLA A*32:01 , HLA B*53:01 , and HLA B*58:01 are risk factors for DILI-DRESS.
Authors
- Huiman X. Barnhart (ORCID: https://orcid.org/0000-0003-0988-3439)
- Raj Vuppalanchi (ORCID: https://orcid.org/0000-0003-0637-1577)
- Yi‐Ju Li (ORCID: https://orcid.org/0000-0001-6996-4834)
- Nitin Arora (ORCID: https://orcid.org/0000-0001-6840-4333)
- Sahand Rahnama‐Moghadam (ORCID: https://orcid.org/0000-0003-1323-5944)
- Elizabeth Jane Phillips (ORCID: https://orcid.org/0000-0002-7623-3383)
- Naga Chalasani (ORCID: https://orcid.org/0000-0003-4082-3178)
- Jiezhun Gu
Institutions
- Duke University (US)
- Vanderbilt University (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.14309/ajg.0000000000003590
- Citations
- 3
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 2.39