Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters
The current study reveals the mechanism by which trypsin promotes PANC-1 cell differentiation into islet-like cells, providing a novel approach for endogenous islet β-cell regeneration.
Authors
- Jiashuang Lai
- Wanjin Hong (ORCID: https://orcid.org/0000-0002-1719-8960)
- Lixia Qian
- Han Chen (ORCID: https://orcid.org/0000-0002-7513-034X)
- Ling Gao (ORCID: https://orcid.org/0000-0002-1704-6545)
- Liangcheng Li
Institutions
- Xiamen University (CN)
- University College London (GB)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-06-13
- DOI
- https://doi.org/10.4239/wjd.v16.i6.102727
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00