Ras homolog enriched in brain 1 regulates β cell mass and β cell function <i>via</i> mTORC1/AMPK/Notch1 pathways
Overall, our findings reveal that Rheb1 regulates β cell proliferation and identity and β-cell development related significant marker, providing a promising novel therapeutic target for diabetes.
Authors
- Yan Yang (ORCID: https://orcid.org/0000-0001-5673-7819)
- Wan-Juan Song
- Jingjing Zhang (ORCID: https://orcid.org/0000-0002-9155-8979)
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-06-13
- DOI
- https://doi.org/10.4239/wjd.v16.i6.104973
- Citations
- 3
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 6.02