The m<sup>6</sup>A writers, readers, and erasers regulate plant development and respond to biotic/abiotic stresses

N6-methyladenosine (m⁶A) is the predominant internal mRNA modification with dynamic and reversible regulation on almost all aspects of mRNA metabolism, including mRNA stability, splicing, and translation. Three m⁶A-related proteins 'writers, readers, and erasers' collaborate to regulate the entire process of m⁶A modification within the organism. The MeRIP-seq technology has expedited research on m⁶A modifications in plants. Although the distribution of m⁶A sites varies across plant species, they are predominantly enriched near the stop codon and within the 3' untranslated region (3'UTR) of mRNAs. Beyond its essential roles in plant growth and development, m⁶A also critically regulates plant responses to biotic and abiotic stresses. This review not only systematically reviews the writers, readers, and erasers associated with m⁶A modification, but also comprehensively summarizes recent advancements in elucidating the significance of m⁶A in plant organ development, floral transition, and fruit ripening. Furthermore, we discuss how m⁶A influences plant-virus relationships and environmental signals. In summary, analyzing m⁶A modification is expected to show promise in creating crop varieties with enhanced yield, quality, and stress tolerance.