Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion
Exosomal miR-425-5p and miR-135b-3p drive CRC progression by promoting immune suppression and vascular permeability. Their inhibition offers a promising strategy for modulating the tumor microenvironment and limiting CRC metastasis.
Authors
- Shuai Zhou (ORCID: https://orcid.org/0000-0002-8755-1192)
- Chunzai Feng
- Silin Ye (ORCID: https://orcid.org/0000-0002-2735-7881)
- Zheng Zheng (ORCID: https://orcid.org/0000-0003-3667-8959)
- Hao Sun (ORCID: https://orcid.org/0000-0002-4329-3910)
- Siquan Zhong
Institutions
- Zhongshan People's Hospital (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-06-13
- DOI
- https://doi.org/10.4251/wjgo.v17.i6.106161
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42