Periodontitis Exacerbates Cognitive Impairment via Endothelial Inflammation: Insights from Single-Nucleus Transcriptomics.
The present study revealed the role of MGLL in linking periodontitis to hippocampal endothelial inflammation and antigen presentation in cognitive impairment. This research will enhance the understanding of how periodontitis impacts cognition and explore potential therapeutic strategies to alleviate periodontitis-associated cognitive impairment.
Authors
- Chuntao Zhao (ORCID: https://orcid.org/0000-0002-2226-3827)
- Jin Yang (ORCID: https://orcid.org/0000-0001-6004-955X)
- Bin Cheng (ORCID: https://orcid.org/0000-0001-7288-806X)
- Zhuowen Shen (ORCID: https://orcid.org/0009-0009-3023-5816)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3290/j.cjdr.b6260577
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00