Comparing tacrolimus level monitoring in peripheral blood mononuclear cells and whole blood within one year after kidney transplantation: a single-center, prospective, observational study
Monitoring tacrolimus levels and IPVs in PBMCs provides greater insight into allograft function and dnDSA status than whole-blood measurements. These findings suggest that PBMC-based tacrolimus monitoring may enhance clinical value in managing kidney transplant recipients.
Authors
- Rui Chen
- Wenmin Xie
- Zhuo Wang (ORCID: https://orcid.org/0009-0007-4566-3018)
- Xuebin Wang (ORCID: https://orcid.org/0000-0003-4270-7330)
- Xue Wang (ORCID: https://orcid.org/0000-0003-2029-2912)
- Jia You
- Yunyun Yang
- Yuhui Chai
- Kaile Zheng
- Lizhi Chen (ORCID: https://orcid.org/0000-0002-6182-5888)
Institutions
- Bengbu Medical College (CN)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Changhai Hospital (CN)
- Shanghai Technical Institute of Electronics & Information (CN)
- Children's Hospital of Fudan University (CN)
- Shanghai Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fphar.2025.1622702
- Citations
- 3
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.96
Funders
- National Natural Science Foundation of China
- Changhai Hospital of Shanghai