Characterization of peripheral immune cells in kidney transplantation recipients under different immunosuppressive treatments
In KTRs, G-MDSCs and M-MDSCs accumulated while functionally activated, naïve-memory T cell populations and HLA-DR<sup>+</sup> monocytes markedly decreased one year after transplantation. Additionally, the number of MDSCs and T cell subsets following transplantation is likely regulated by mTOR inhibitors.
Authors
- Junlong Zhang (ORCID: https://orcid.org/0000-0003-1352-7672)
- Haohan Zhang (ORCID: https://orcid.org/0000-0002-4827-4217)
- Bei Cai (ORCID: https://orcid.org/0000-0002-2597-4915)
- Yi Li (ORCID: https://orcid.org/0000-0003-0418-3521)
- Yu Fan (ORCID: https://orcid.org/0000-0001-6660-1747)
- Weihua Feng
- Yunze Tai
- Yao Luo (ORCID: https://orcid.org/0000-0002-4542-3504)
- Niu Li (ORCID: https://orcid.org/0000-0003-1887-6900)
- Lin Yan
- Jiwen Fan (ORCID: https://orcid.org/0000-0001-5280-4391)
- H. T. Long
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1605664
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Sichuan Province