Identifying key genes associated with recurrence in non-small cell lung cancer through TCGA and single-cell analysis

The differentially expressed genes primarily influence NSCLC recurrence through involvement in biological processes related to metabolism and hormone secretion pathways. Notably, the KCNA7 and FOX gene families were identified as critical for NSCLC recurrence. This study highlights specific genes within proliferation and cell cycle pathways as key therapeutic targets for managing NSCLC recurrence.