Stemness-driven clusters in ovarian cancer: immune characteristics and prognostic implications
This study establishes a novel stemness-related gene signature for prognosis prediction and therapeutic stratification in OC. AKAP12 was identified as a potential biomarker and therapeutic target, offering new avenues for precision treatment in stemness-driven OC.
Authors
- Ping Li
- Xiaorui Wu
- Xinyan Zeng
- Xiaoqin Li (ORCID: https://orcid.org/0000-0003-3762-9817)
- Yingying Du (ORCID: https://orcid.org/0000-0002-0513-2569)
- Wentian Wu
Institutions
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fonc.2025.1577283
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00