Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway
These findings suggest that celastrol improves endothelial function by inhibiting ER stress and increasing NO production through the activation of the AMPK pathway in DIO mice.
Authors
- Wenkun Liu
- Yu Huang (ORCID: https://orcid.org/0000-0003-1500-0989)
- Hongjin Liu (ORCID: https://orcid.org/0000-0001-5625-2395)
- Jing Yang (ORCID: https://orcid.org/0000-0001-8855-6254)
- Weihong Lin
- Litao Wang (ORCID: https://orcid.org/0009-0004-0706-9534)
- Lei Chen (ORCID: https://orcid.org/0000-0003-0018-9993)
- Yu Cheng (ORCID: https://orcid.org/0000-0001-8335-9403)
- Yong Lin
- Qiong Jiang (ORCID: https://orcid.org/0000-0002-5962-8180)
- Lianglong Chen (ORCID: https://orcid.org/0000-0003-0306-0976)
Institutions
- Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1186/s10020-025-01259-6
- Citations
- 2
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province
- Fujian Medical University