AliC and AliD of nonencapsulated Streptococcus pneumoniae enhance virulence in a Galleria mellonella model of infection by contributing to reactive oxygen species resistance
This research demonstrates that proteins encoded by genes regulated by AliC and AliD alter susceptibility to host-derived mechanisms for bacterial clearance and increases bacterial survival in response to ROS.
Authors
- Courtney D. Thompson
- Lori E. Crosby (ORCID: https://orcid.org/0000-0001-6656-7745)
- Lance E. Keller (ORCID: https://orcid.org/0000-0002-8779-9278)
- Ana G. Jop Vidal (ORCID: https://orcid.org/0009-0005-0785-0889)
- Md. Robin Khan
- Larry S. McDaniel (ORCID: https://orcid.org/0000-0002-1649-7563)
- Shelby G. Holcomb
- Jorge Eugenio Vidal (ORCID: https://orcid.org/0000-0003-0573-5658)
Institutions
- University of Mississippi Medical Center (US)
- Mississippi College (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fcimb.2025.1583375
- Citations
- 2
- Primary Topic
- Aquaculture disease management and microbiota
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Institutes of Health