Plasma proteomic profiling of hospitalized patients co-infected with HIV and SARS-CoV-2
The proteomic profile highlighted the disruption caused by COVID-19 in immunomodulation, thrombosis, and viral entry pathways in PLWH. Further validation of these signatures could improve risk stratification and tailored interventions for this vulnerable patient cohort.
Authors
- Tangkai Qi (ORCID: https://orcid.org/0000-0002-3771-2488)
- Renfang Zhang
- Jiangrong Wang (ORCID: https://orcid.org/0000-0002-0001-503X)
- Jinfeng Sun (ORCID: https://orcid.org/0000-0001-6356-1786)
- Yinzhong Shen (ORCID: https://orcid.org/0000-0002-7604-5139)
- Yang Tang (ORCID: https://orcid.org/0000-0001-7201-4231)
- Zichen Song (ORCID: https://orcid.org/0000-0002-3045-5466)
- Jingna Xun (ORCID: https://orcid.org/0000-0002-6086-6960)
- Junyang Yang
- Yueming Shao (ORCID: https://orcid.org/0000-0003-3501-7729)
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-5979-244X)
- Li Liu (ORCID: https://orcid.org/0000-0002-5265-4159)
- Jun Chen (ORCID: https://orcid.org/0000-0002-6946-3623)
- Jianjun Sun (ORCID: https://orcid.org/0000-0001-5780-5334)
- Zhenyan Wang
- Shuibao Xu
- Wei Song (ORCID: https://orcid.org/0009-0006-6233-6759)
Institutions
- Fudan University (CN)
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1601672
- Citations
- 3
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- Shanghai Municipal Health Commission
- Science and Technology Commission of Shanghai Municipality
- Shanghai Hospital Development Center