Advanced Solutions for Native Lung Hyperinflation: Endobronchial Valves in Post Transplant Care

Background: Native lung hyperinflation (NLH) is a potential late complication in patients with chronic obstructive pulmonary disease (COPD) following single lung transplantation, characterized by radiologic evidence of native lung expansion, mediastinal shift, and respiratory deterioration. The progressive dynamics of NLH and its detrimental effect on graft function serve as reminders of the imperative to address this condition. Few effective treatments exist for NLH, and the most common option is lung volume reduction surgery (LVRS). Conversely, endobronchial valves (EBV) are a potential treatment option for NLH. This case series describes two post-transplant patients successfully treated with EBVs, highlighting the benefits and limitations of this approach.