The new assay type IV collagen 7S (CLEIA) is a useful test to identify progressive fibrosis in chronic liver disease: A study based on magnetic resonance elastography
The novel assay, type IV collagen 7S, is a highly effective and noninvasive biomarker for liver fibrosis. The performance of type IV collagen 7S tends to have robustness under the difference of ALT. Its combination with the FIB-4 index enhances diagnostic precision, particularly in intermediate-risk patients, reinforcing its role in refining fibrosis staging and optimizing patient management.
Authors
- Ken Haruma (ORCID: https://orcid.org/0000-0002-2188-0401)
- Miwa Kawanaka (ORCID: https://orcid.org/0000-0003-2341-5199)
- Hirofumi Kawamoto (ORCID: https://orcid.org/0000-0002-9650-3555)
- Noriyo Urata
- Takashi Fushimi (ORCID: https://orcid.org/0000-0002-2872-1198)
- Tomohiro Tanikawa (ORCID: https://orcid.org/0000-0001-9766-9007)
- Motoyuki Otsuka (ORCID: https://orcid.org/0000-0003-2869-2881)
Institutions
- Okayama University (JP)
- Kawasaki Medical School (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1111/hepr.14202
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35