Time saved in activities of daily living and whole‐brain volume: Post hoc analysis of a randomized feasibility trial of gamma oscillation treatment in participants with mild or moderate Alzheimer's disease
Evoked gamma oscillation slows functional loss and brain atrophy in Alzheimer's disease.Slowing of functional and cognitive decline and brain atrophy worsening can be expressed as time saved.Evoked gamma oscillation saves 4.83 months of progression in activities of daily living, 4.59 months of progression in Mini-Mental State Examination, and 4.09 months of decline in whole-brain volume over 6 months.
Authors
- Suzanne Hendrix (ORCID: https://orcid.org/0000-0002-2374-7727)
- Matthew Morgan (ORCID: https://orcid.org/0000-0001-6691-8488)
- Mihály Hajós (ORCID: https://orcid.org/0000-0002-5379-8576)
- Julia N. Riddle
- Craig Mallinckrodt
- Benjamin Haaland (ORCID: https://orcid.org/0000-0002-6270-6303)
- Jessie Nicodemus‐Johnson
- Chandran Seshagiri
- R. Kern (ORCID: https://orcid.org/0000-0003-0640-122X)
- Samuel P. Dickson (ORCID: https://orcid.org/0000-0002-4622-1349)
- Joshua R. Christensen
- Lily Lee
- Christopher I. Howell
- Marwan N. Sabbagh
Institutions
- Barrow Neurological Institute (US)
- TetraLogic Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/trc2.70118
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43