Lichen sclerosus epidemiology in girls from the Republic of Bashkortostan

Aim : to study the features of lichen sclerosus (LS) epidemiology in girls from the Republic of Bashkortostan (RB). Materials and Methods . A retrospective cohort study was conducted. The authors analyzed LS incidence in girls aged 0 to 18 years, the data provided by two pediatric gynecological department, which in different years served all RB girls with gynecological pathology. A comparison of indicators recorded during the two equal and comparable time periods was carried out: the first 9 years of operation (from 1996 to 2004) at the Department of Pediatric Gynecology of the Clinical Hospital of Emergency Medical Care, Ufa and the first 9 years of operation (from 2015 to 2023) at the Gynecological Department of the Republican Children's Clinical Hospital, Ufa. Results . Lichen sclerosus in RB girls can be attributed to orphan disease, since its incidence rate over the past 9 years comprised 0.46 ‰. Over the 19-year follow-up (2004–2023), the accumulated LS incidence in RB girls aged 0 to 18 years increased from 0.22 to 0.46 ‰, and in Ufa – from 0.35 to 0.65 ‰. Conclusion . In recent years, a significant increase in LS incidence in girls has been observed in the RB. Most LS patients are in the prepubertal childhood period.