Multifactorial influence of type 2 diabetes on cardiovascular risk assessed by PolSCORE, SCORE2 in the age group 40–69 years

Introduction and Objective.Cardiovascular risk (CV risk) is the probability of developing cardiovascular disease or dying from it within a specified period of time.One of the main factors increasing this risk is diabetes (DM).The aim of the study was to assess the effect of type 2 diabetes (T2DM) on CV risk based on the SCORE and SCORE2 scales, taking other factors into account.Materials and Method.The study was conducted in a group of 1,540 people aged 40-89 years (226 people with diabetes -T2DM(+)).The following scales were used to assess CV risk: Pol-SCORE and SCORE2.Inclusion criterion was the absence of cardiovascular complications such as: myocardial infarction, overt coronary artery disease, previous stroke, renal failure or complications of T2DM.Results.In the T2DM(+) group, high and very high CV risk was more frequently noted (Pol-SCORE: 26.1% and 34.5%; SCORE2: 24.3% and 42.5%) compared to T2DM(-).The regression model included an analysis of 10 factors determining CV risk.In estimating CV risk using the Pol-SCORE scale, 8 factors were most important (P=0.86), in the SCORE2 scale a total of 3 factors (TC -total cholesterol; LDL; TGs -triglyceride).In the T2DM(+) group, age(r=0.53)and TC(r=0.43)showed the strongest positive correlation with SCORE2, while for Pol-SCORE -age(r=0.05).Conclusions.In the CV risk assessment using the Pol-SCORE scale, the following were of significant importance: TC, HDL, LDL, TGs, non-HDL, systolic pressure, diastolic pressure, heart rate.In the risk assessment using the SCORE2 scale, the following were significant: total cholesterol and triglyceride.Diagnosed T2DM significantly increases CV risk.