Multicenter retrospective comparison of safety and efficacy among three antithrombotic regimens following TAVI
Each antithrombotic regimen presented unique clinical benefits and limitations. Transitioning from warfarin to rivaroxaban was associated with a significantly reduced risk of bleeding and shorter hospital stays. Transitioning from dual antiplatelet therapy to aspirin monotherapy significant prolonged APTT without increasing clinical bleeding events. These findings highlight the importance of tailored antithrombotic strategies to optimize post-TAVI outcomes.
Authors
- Suchun Wang
- Zhengli Jiang
- Yu Ren (ORCID: https://orcid.org/0000-0003-2928-138X)
- Jing Chen (ORCID: https://orcid.org/0000-0002-4037-7158)
- Hua Luo (ORCID: https://orcid.org/0000-0002-6643-5299)
Institutions
- Wenzhou Medical University (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fphar.2025.1531361
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Plan Project of Taizhou