Multicenter retrospective comparison of safety and efficacy among three antithrombotic regimens following TAVI

Each antithrombotic regimen presented unique clinical benefits and limitations. Transitioning from warfarin to rivaroxaban was associated with a significantly reduced risk of bleeding and shorter hospital stays. Transitioning from dual antiplatelet therapy to aspirin monotherapy significant prolonged APTT without increasing clinical bleeding events. These findings highlight the importance of tailored antithrombotic strategies to optimize post-TAVI outcomes.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-06-11
DOI
https://doi.org/10.3389/fphar.2025.1531361
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Multicenter retrospective comparison of safety and efficacy among three antithrombotic regimens following TAVI

Suchun Wang, Zhengli Jiang, Yu Ren, Jing Chen et al.
Frontiers in Pharmacology
Cardiac Valve Diseases and Treatments
article

Multicenter retrospective comparison of safety and efficacy among three antithrombotic regimens following TAVI

Suchun Wang, Zhengli Jiang, Yu Ren, Jing Chen, Hua Luo
article en

Abstract

Each antithrombotic regimen presented unique clinical benefits and limitations. Transitioning from warfarin to rivaroxaban was associated with a significantly reduced risk of bleeding and shorter hospital stays. Transitioning from dual antiplatelet therapy to aspirin monotherapy significant prolonged APTT without increasing clinical bleeding events. These findings highlight the importance of tailored antithrombotic strategies to optimize post-TAVI outcomes.

Frontiers in PharmacologyVol. 16
Wenzhou Medical University (CN), Zhejiang Taizhou Hospital (CN)
Science and Technology Plan Project of Taizhou
Openalex Percentile: Top 76%
Cardiac Valve Diseases and Treatments
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