Comparative evaluation of the efficacy of “advanced platelet-rich fibrin plus” and enamel matrix derivative on proliferation and migration of periodontal ligament fibroblasts – An in vitro study

The combined application of A-PRF+ and EMD promoted enhanced wound healing, surpassing the effects of EMD and A-PRF+ used individually. The study also demonstrated the superior ability of EMD alone in periodontal fibroblast healing. Cell migration and proliferation propensity of A-PRF+ endorse it as an option for regenerative therapy.