Candida glabrata Prosthetic Joint Infection Managed with Ibrexafungerp

We report a case of a triazole and echinocandin-resistant <i>C. glabrata</i> right shoulder prosthetic joint infection in a 60-year-old woman. The patient underwent surgery and received the novel triterpenoid antifungal agent ibrexafungerp. She initially improved, but relapsed four months post-treatment. This case highlights the potential role of ibrexafungerp in multidrug-resistant <i>Candida</i> infections.

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Publication Details

Journal
Journal of Fungi
Published
2025-06-11
DOI
https://doi.org/10.3390/jof11060442
Citations
1
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
1.40
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article

Candida glabrata Prosthetic Joint Infection Managed with Ibrexafungerp

Paschalis Vergidis, Jack McHugh, Ella Nadarevic
1 citations
Journal of Fungi
Antifungal resistance and susceptibility
1.40
article

Candida glabrata Prosthetic Joint Infection Managed with Ibrexafungerp

Paschalis Vergidis, Jack McHugh, Ella Nadarevic
article en
1 citations

Abstract

We report a case of a triazole and echinocandin-resistant <i>C. glabrata</i> right shoulder prosthetic joint infection in a 60-year-old woman. The patient underwent surgery and received the novel triterpenoid antifungal agent ibrexafungerp. She initially improved, but relapsed four months post-treatment. This case highlights the potential role of ibrexafungerp in multidrug-resistant <i>Candida</i> infections.

Journal of FungiVol. 11(6)
Mayo Clinic in Florida (US)
Good health and well-being
Openalex Percentile: Top 20%
Antifungal resistance and susceptibility
1.40
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