MANAGEMENT OF SEVERE HYPERTRIGLYCERIDEMIA IN PREGNANCY: CASE REPORT AND THERAPEUTIC STRATEGIES

Severe hypertriglyceridemia (HTG) during pregnancy is a rare but serious complication, especially in patients with pre-existing dyslipidemia. This condition carries a high risk of acute pancreatitis, obstetric complications, and increased maternal-fetal morbidity. We report the case of a pregnant woman with familial hypertriglyceridemia who developed acute pancreatitis during pregnancy, requiring multidisciplinary management. The therapeutic approach included strict dietary modification, high-dose omega-3 supplementation, and plasmapheresis, which led to a rapid reduction in triglyceride levels and clinical improvement. This case highlights the importance of close monitoring and early intervention in at-risk patients to prevent severe maternal and fetal complications. Personalized management combining dietary measures, appropriate pharmacological therapy, and extracorporeal techniques remains the cornerstone of treatment for severe HTG during pregnancy.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-05-31
DOI
https://doi.org/10.21474/ijar01/20917
Primary Topic
Lipid metabolism and disorders
Type
article
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article

MANAGEMENT OF SEVERE HYPERTRIGLYCERIDEMIA IN PREGNANCY: CASE REPORT AND THERAPEUTIC STRATEGIES

Oussama Jaddi, Sara Ijdda, Eleazar Niyogushima, G. El Mghari et al.
International Journal of Advanced Research
Lipid metabolism and disorders
article

MANAGEMENT OF SEVERE HYPERTRIGLYCERIDEMIA IN PREGNANCY: CASE REPORT AND THERAPEUTIC STRATEGIES

Oussama Jaddi, Sara Ijdda, Eleazar Niyogushima, G. El Mghari, Sana Rafi, Nawal El Ansari
article en

Abstract

Severe hypertriglyceridemia (HTG) during pregnancy is a rare but serious complication, especially in patients with pre-existing dyslipidemia. This condition carries a high risk of acute pancreatitis, obstetric complications, and increased maternal-fetal morbidity. We report the case of a pregnant woman with familial hypertriglyceridemia who developed acute pancreatitis during pregnancy, requiring multidisciplinary management. The therapeutic approach included strict dietary modification, high-dose omega-3 supplementation, and plasmapheresis, which led to a rapid reduction in triglyceride levels and clinical improvement. This case highlights the importance of close monitoring and early intervention in at-risk patients to prevent severe maternal and fetal complications. Personalized management combining dietary measures, appropriate pharmacological therapy, and extracorporeal techniques remains the cornerstone of treatment for severe HTG during pregnancy.

International Journal of Advanced ResearchVol. 13(05)
Openalex Percentile: Top 76%
Lipid metabolism and disorders
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