Focal Autonomic Seizures Manifesting With Prevailing Signs of Gastrointestinal Disorder in Dogs

In human medicine, focal seizures can clinically express as autonomic signs, such as gastrointestinal dysfunction, cardiovascular changes, and variation of pupillary size; but little is known about possible presentations of autonomic seizures in veterinary medicine. Three dogs were presented for recurrent episodes characterized by hypersalivation, vomiting, retching, and signs of abdominal discomfort. Neurological examinations were normal between episodes. Electroencephalographic (EEG) recordings identified ictal or interictal epileptiform discharges in all dogs. Based on clinical signs and EEG findings, a diagnosis of focal autonomic seizures was made. There was a notable positive response of clinical signs to antiepileptic treatment. These cases highlight the diverse clinical presentations of focal autonomic seizures in dogs and emphasize the diagnostic value of EEG in these cases.

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Publication Details

Journal
Journal of Veterinary Internal Medicine
Published
2025-06-11
DOI
https://doi.org/10.1111/jvim.70158
Primary Topic
Epilepsy research and treatment
Type
article
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article

Focal Autonomic Seizures Manifesting With Prevailing Signs of Gastrointestinal Disorder in Dogs

Elsa Lyon, Nicolas Van Caenegem, Catherine Escriou, Stéphane Blot et al.
Journal of Veterinary Internal Medicine
Epilepsy research and treatment
article

Focal Autonomic Seizures Manifesting With Prevailing Signs of Gastrointestinal Disorder in Dogs

Elsa Lyon, Nicolas Van Caenegem, Catherine Escriou, Stéphane Blot, Valérie Freiche, S.N. Diop
article en

Abstract

In human medicine, focal seizures can clinically express as autonomic signs, such as gastrointestinal dysfunction, cardiovascular changes, and variation of pupillary size; but little is known about possible presentations of autonomic seizures in veterinary medicine. Three dogs were presented for recurrent episodes characterized by hypersalivation, vomiting, retching, and signs of abdominal discomfort. Neurological examinations were normal between episodes. Electroencephalographic (EEG) recordings identified ictal or interictal epileptiform discharges in all dogs. Based on clinical signs and EEG findings, a diagnosis of focal autonomic seizures was made. There was a notable positive response of clinical signs to antiepileptic treatment. These cases highlight the diverse clinical presentations of focal autonomic seizures in dogs and emphasize the diagnostic value of EEG in these cases.

Journal of Veterinary Internal MedicineVol. 39(4)
Inserm (FR), École Nationale Vétérinaire d'Alfort (FR), Université Paris-Est Créteil (FR), Paris-Est Sup (FR), Clinique des Cèdres (FR), VetAgro Sup (FR), Clinique de l'Yvette (FR), Institut Mondor de Recherche Biomédicale (FR)
Good health and well-being
Openalex Percentile: Top 84%
Epilepsy research and treatment
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