The frequency of neurological and psychological disorders in patients with bullous pemphigoid

Background & Aims: Bullous pemphigoid is the most common autoimmune blistering skin disease, primarily affecting the elderly, and has been associated with neurological and psychological comorbidities.This study aimed to investigate the prevalence of these disorders in patients with bullous pemphigoid and explore the potential relationship between bullous pemphigoid and neurological/psychological diseases. Materials & Methods:This was a retrospective cross-sectional analytical study involving 100 patients with bullous pemphigoid admitted to Sinai Hospital in Tabriz over a ten-year period (2012-2022).Data were extracted from patient records and analyzed using SPSS software.Results: The mean age of the patients was 73.12 years.Forty-two percent (42%) were male, and 58% were female.Sixty-seven percent (67%) had at least one neurological or psychological disorder.The most common neurological disease was stroke (26%), while the least common was Parkinson's disease (1%).Depression was observed in 15% of patients. Conclusion:The findings indicate a high prevalence of neurological and psychological disorders in patients with bullous pemphigoid.Early diagnosis and management of these comorbidities may improve patients' quality of life.