Monkeypox: Difficulties and Prospects for Worldwide Disease Management

Monkeypox (MPX) has become a global public health problem. This zoonotic viral disease, characterized by rash, lymphadenopathy, and fever, used to be restricted to Central and West Africa. However, recent outbreaks have increased its global reach. This study examined the problems and opportunities for MPX control. Articles published from 2013 to 2023 were included in this investigation while excluding the ones that were unavailable in the general library or were only available in conference abstract form. MPX is transmitted through close contact with infected animals. Medically proven, it can be tested with polymerase chain reaction (PCR). Nonetheless, there is no specific treatment for this type of disease. Only supportive measures can be taken in this regard, and smallpox vaccination offers some protection against MPX. Accordingly, international financial support should be allocated to studies on this disease in order to develop safer vaccines, take more holistic health approaches to prevent human-to-human transmission, and put suitable surveillance systems in place.

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Publication Details

Journal
Avicenna Journal of Clinical Microbiology and Infection
Published
2025-03-30
DOI
https://doi.org/10.34172/ajcmi.3580
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
0.00
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article

Monkeypox: Difficulties and Prospects for Worldwide Disease Management

Sina Samenezhad, Dorna Rafighi, Ali Khodadadeh Jigheh
Avicenna Journal of Clinical Microbiology and Infection
Poxvirus research and outbreaks
article

Monkeypox: Difficulties and Prospects for Worldwide Disease Management

Sina Samenezhad, Dorna Rafighi, Ali Khodadadeh Jigheh
article en

Abstract

Monkeypox (MPX) has become a global public health problem. This zoonotic viral disease, characterized by rash, lymphadenopathy, and fever, used to be restricted to Central and West Africa. However, recent outbreaks have increased its global reach. This study examined the problems and opportunities for MPX control. Articles published from 2013 to 2023 were included in this investigation while excluding the ones that were unavailable in the general library or were only available in conference abstract form. MPX is transmitted through close contact with infected animals. Medically proven, it can be tested with polymerase chain reaction (PCR). Nonetheless, there is no specific treatment for this type of disease. Only supportive measures can be taken in this regard, and smallpox vaccination offers some protection against MPX. Accordingly, international financial support should be allocated to studies on this disease in order to develop safer vaccines, take more holistic health approaches to prevent human-to-human transmission, and put suitable surveillance systems in place.

Avicenna Journal of Clinical Microbiology and InfectionVol. 12(1)
Islamic Azad University Central Tehran Branch (IR), Shahid Beheshti University of Medical Sciences (IR)
Openalex Percentile: Top 86%
Poxvirus research and outbreaks
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Monkeypox: Difficulties and Prospects for Worldwide Disease Management — Sina Samenezhad, Dorna Rafighi, et al. · Avicenna Journal of Clinical Microbiology and Infection (2025) | TGRS Research Map | TGRS