The Performance of the Endurant Endoprosthesis in an Infrarenal Aortic Aneurysm with a Wide or Conical-Shaped Infrarenal Neck Anatomy

<b>Background/Objectives:</b> Wide and conical-shaped infrarenal necks are risk factors for neck-related complications after Endovascular Aorta Aneurysm Repair (EVAR). The aim of this study is to investigate the performance of the Endurant endoprosthesis in wide/conical-shaped aortic neck anatomies compared to its performance in a normal infrarenal neck (reference group). <b>Methods</b>: A single-center, retrospective observational cohort study was performed, including consecutive subjects with an infrarenal abdominal aortic aneurysm, treated electively with an Endurant endoprosthesis. The primary endpoint was the freedom from aneurysm-related reinterventions through 1 year. Secondary endpoints included proximal fixation failure, type IA endoleak, stent migration, aneurysm sac remodeling, aneurysm-related mortality, freedom from reinterventions throughout available follow-up, and rupture. <b>Results</b>: A total of 268 patients were included, with a mean age of 73.3 years, and 85.1% were male. Freedom from aneurysm-related reinterventions was significantly lower in the wide-neck group (60.0%) compared to the reference group (81.1%; <i>p</i> = 0.018) but not for the conical-neck group (70.3%; <i>p</i> = 0.286). Median time to first reintervention was 1.7 (IQR 0.8; 4.4 years) in the reference group, 2.9 years (IQR 0.3; 5.0 years) in the wide-neck group (<i>p</i> = 0.547) and 3.8 years (IQR 0.4; 6.5) in the conical-neck group (<i>p</i> = 0.123). The proximal fixation failure rate was 7.4% in the wide-neck group compared to 3.3% in the reference group (<i>p</i> = 0.155) and 1.7% in the conical-neck group (<i>p</i> = 0.525). The type IA endoleak rate was 4.9% in the wide-neck group versus 3.3% in the reference group (<i>p</i> = 0.250). <b>Conclusions</b>: In the group with wide necks, reintervention-free survival was lower compared to the reference group, which seems to be driven by proximal fixation failure.

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Journal
Journal of Clinical Medicine
Published
2025-06-11
DOI
https://doi.org/10.3390/jcm14124133
Primary Topic
Aortic aneurysm repair treatments
Type
article
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article

The Performance of the Endurant Endoprosthesis in an Infrarenal Aortic Aneurysm with a Wide or Conical-Shaped Infrarenal Neck Anatomy

Michel M.P.J. Reijnen, Armelle J.A. Meershoek, Daphne van der Veen, Suzanne Holewijn et al.
Journal of Clinical Medicine
Aortic aneurysm repair treatments
article

The Performance of the Endurant Endoprosthesis in an Infrarenal Aortic Aneurysm with a Wide or Conical-Shaped Infrarenal Neck Anatomy

Michel M.P.J. Reijnen, Armelle J.A. Meershoek, Daphne van der Veen, Suzanne Holewijn, Maaike Plug
article en

Abstract

<b>Background/Objectives:</b> Wide and conical-shaped infrarenal necks are risk factors for neck-related complications after Endovascular Aorta Aneurysm Repair (EVAR). The aim of this study is to investigate the performance of the Endurant endoprosthesis in wide/conical-shaped aortic neck anatomies compared to its performance in a normal infrarenal neck (reference group). <b>Methods</b>: A single-center, retrospective observational cohort study was performed, including consecutive subjects with an infrarenal abdominal aortic aneurysm, treated electively with an Endurant endoprosthesis. The primary endpoint was the freedom from aneurysm-related reinterventions through 1 year. Secondary endpoints included proximal fixation failure, type IA endoleak, stent migration, aneurysm sac remodeling, aneurysm-related mortality, freedom from reinterventions throughout available follow-up, and rupture. <b>Results</b>: A total of 268 patients were included, with a mean age of 73.3 years, and 85.1% were male. Freedom from aneurysm-related reinterventions was significantly lower in the wide-neck group (60.0%) compared to the reference group (81.1%; <i>p</i> = 0.018) but not for the conical-neck group (70.3%; <i>p</i> = 0.286). Median time to first reintervention was 1.7 (IQR 0.8; 4.4 years) in the reference group, 2.9 years (IQR 0.3; 5.0 years) in the wide-neck group (<i>p</i> = 0.547) and 3.8 years (IQR 0.4; 6.5) in the conical-neck group (<i>p</i> = 0.123). The proximal fixation failure rate was 7.4% in the wide-neck group compared to 3.3% in the reference group (<i>p</i> = 0.155) and 1.7% in the conical-neck group (<i>p</i> = 0.525). The type IA endoleak rate was 4.9% in the wide-neck group versus 3.3% in the reference group (<i>p</i> = 0.250). <b>Conclusions</b>: In the group with wide necks, reintervention-free survival was lower compared to the reference group, which seems to be driven by proximal fixation failure.

Journal of Clinical MedicineVol. 14(12)
Rijnstate Hospital (NL), University of Twente (NL)
Good health and well-being
Openalex Percentile: Top 78%
Aortic aneurysm repair treatments
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