The effect of Zuogui-Jiangtang-Yishen decoction on the intestinal flora’s response to L-α-phosphatidylcholine and L-tyrosine in patients with diabetic kidney disease: an in vitro study
ZGJTYS was found to effectively restore the microbiota that were altered by L-α-phosphatidylcholine and L-tyrosine to normal, along with their metabolites. However, the mechanism by which ZGJTYS exerts its preventive and therapeutic effects on DKD through the gut microbiota still requires further study.
Authors
- Changhui Zhao (ORCID: https://orcid.org/0000-0002-1882-7490)
- Qin Xiang (ORCID: https://orcid.org/0000-0001-8972-4117)
- Yeshi Yin (ORCID: https://orcid.org/0000-0001-6866-5525)
- Xiaobo Sharon Hu (ORCID: https://orcid.org/0000-0002-6636-9738)
- Xiu Liu (ORCID: https://orcid.org/0000-0001-7818-8312)
- Zongyan Li (ORCID: https://orcid.org/0000-0002-8196-7269)
- Rong Yu (ORCID: https://orcid.org/0000-0002-7950-218X)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Guangxi University (CN)
- Hunan University of Science and Engineering (CN)
- The Fourth People's Hospital (CN)
- Taizhou Fourth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fphar.2025.1573514
- Citations
- 2
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.59
Funders
- National Natural Science Foundation of China