Targeting Azole-Resistant Candida albicans: Tetrapeptide Tuftsin-Modified Liposomal Vaccine Induces Superior Immune Protection
Tuft-lip-WCAg formulation is a safe, immunogenic, and highly effective vaccine candidate that offers complete protection against drug-resistant <i>C. albicans</i> in a murine model. These findings support its promise as a novel immunoprophylactic strategy, particularly for immunocompromised populations at high risk of invasive candidiasis.
Authors
- Basmah F. Alharbi (ORCID: https://orcid.org/0000-0001-6863-469X)
- Abdullah M. Alnuqaydan (ORCID: https://orcid.org/0000-0001-9306-609X)
- Masood Alam Khan (ORCID: https://orcid.org/0000-0003-4031-4189)
- Arif Khan (ORCID: https://orcid.org/0000-0002-4528-2668)
- Aqel Albutti (ORCID: https://orcid.org/0000-0001-8697-5340)
- Mohammad Owais (ORCID: https://orcid.org/0000-0001-7377-7388)
Institutions
- Qassim University (SA)
- Aligarh Muslim University (IN)
Publication Details
- Journal
- Vaccines
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3390/vaccines13060630
- Citations
- 3
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 4.19