Anti-Inflammatory effects of Lactobacillus helveticus and Arthrospira platensis on colonic cells inflamed by Crohn’s disease-associated Escherichia coli
L. helveticus and HA-A. platensis synergistically inhibit CD-associated E. coli pathogenicity and modulate inflammatory responses in vitro. These findings highlight their potential as adjunctive therapies for CD, warranting further preclinical validation.
Authors
- Nastaran Asri (ORCID: https://orcid.org/0000-0002-1986-615X)
- Leila Pishkar (ORCID: https://orcid.org/0000-0002-1499-4793)
- Mohammad Rostami‐Nejad (ORCID: https://orcid.org/0000-0003-2495-1831)
- Hamidreza Houri (ORCID: https://orcid.org/0000-0002-6813-0229)
- Samira Alipour
- Hossein Halimi
Institutions
- Research Institute for Endocrine Sciences (IR)
- Islamic Azad University Islamshahr Branch (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Molecular and Cell Biology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1186/s12860-025-00545-9
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Shahid Beheshti University of Medical Sciences
- Research Institute for Gastroenterology and Liver Diseases