Is Functional Surgery the Treatment of Choice for Subungual Melanoma in Situ and Subungual Microinvasive Melanoma? A Retrospective Cohort Study in a Latin American Population

Of 45 NUM cases, 15 were men and 30 women. Lesions were more common on toenails (53.3%). Thirteen patients underwent amputation, whereas 32 had FS. The median follow-up was 52 months, with no regional recurrence, metastasis, or death. One local recurrence occurred in a patient initially treated with amputation. Conclusion: This study found no significant differences in recurrence, metastasis, or survival between FS and amputation. Although both interventions result in low recurrence and high survival rates, FS is preferred because of better cosmetic and functional outcomes.