Wire Injury-Induced Moderate Aortic Valve Stenosis in Mice Is Accompanied by a Chronic Systemic Inflammatory Reaction
The results suggest a link between number and activation state of leukocytes in peripheral organs and cardiac processes in AS. Considering the pathological value of inflammation, it is crucial that future studies investigate if a modulation of the systemic inflammatory reaction relieves severity of AS and opposes development of heart failure.
Authors
- K Becker (ORCID: https://orcid.org/0000-0001-6876-6035)
Institutions
- University of Cologne (DE)
- Düsseldorf University Hospital (DE)
- University Hospital Cologne (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Cells
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3390/cells14120883
- Citations
- 2
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Deutsche Forschungsgemeinschaft