Utility of peripheral blood oxygen saturation (SpO <sub>2</sub> )/fraction of inspired oxygen (FiO <sub>2</sub> ) ratio and arterial partial oxygen pressure (PaO <sub>2</sub> )/FiO <sub>2</sub> ratio in the diagnosis of acute respiratory distress syn
Our study determined the reliability of using the ratio of peripheral blood oxygen saturation (SpO<sub>2</sub>) and the fraction of inspired oxygen (FiO<sub>2</sub>) rather than the ratio of arterial partial oxygen pressure (PaO<sub>2</sub>) and FiO<sub>2</sub> for diagnosing acute respiratory distress syndrome (ARDS). Pulse oximetry and arterial blood gas analysis were performed to obtain both ratios, respectively, in 70 patients who fulfilled the Berlin definition criteria of ARDS. A detailed history, clinical examination, and relevant evaluation were done. There was a significant correlation between the two ratios. The former had a lower sensitivity and specificity than the latter. Thus, the SpO<sub>2</sub>/FiO<sub>2</sub> ratio is a reliable, straightforward, non-invasive, and readily available marker for diagnosing the presence and severity of ARDS, and may be used as an alternative to the PaO<sub>2</sub>/FiO<sub>2</sub> ratio in resource-limited settings.
Authors
- Sharad Chawla
- Rajesh Kakkar
- Sushant Khanduri (ORCID: https://orcid.org/0000-0002-4877-860X)
- Reshma Kaushik
- Rajeev Mohan Kaushik (ORCID: https://orcid.org/0000-0003-0217-4269)
- Sushil Rathi
Institutions
- Swami Rama Himalayan University (IN)
- Himalayan Institute of Yoga Science and Philosophy (US)
- Institute of Medical Sciences (IN)
Publication Details
- Journal
- Tropical Doctor
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1177/00494755251349071
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Swami Rama Himalayan University