Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function
FOXP3 is expressed on both CD19<sup>+</sup>CD39<sup>-</sup> and CD19<sup>+</sup>CD39<sup>+</sup> B lymphocytes. CD19<sup>+</sup>CD39<sup>-</sup> cells showed high levels of IL-10 and low levels of FOXP3 mRNA. CD19<sup>+</sup>CD39<sup>-</sup> B cells decreased the Th1 cells and were associated with β-cell function.
Authors
- Mariana Haydee García-Hernández (ORCID: https://orcid.org/0000-0002-9244-5706)
- Edith Elena Uresti‐Rivera (ORCID: https://orcid.org/0000-0003-4760-8841)
- Fátima de Lourdes Ochoa-González
- Juan Manuel Vargas‐Morales (ORCID: https://orcid.org/0000-0001-5959-7815)
- Diana Patricia Portales‐Pérez (ORCID: https://orcid.org/0000-0001-8063-7869)
- Edgar Eduardo Lara-Ramirez (ORCID: https://orcid.org/0000-0001-7112-3233)
- Bruno Rivas‐Santiago (ORCID: https://orcid.org/0000-0002-1521-1519)
- Abraham Cardenas-Juarez
- Flor Itzel Lira-Hernández
Institutions
- Autonomous University of San Luis Potosí (MX)
- Universidad Autónoma de Zacatecas "Francisco García Salinas" (MX)
- Instituto Politécnico Nacional (MX)
- Autonomous University of Tamaulipas (MX)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1080/08820139.2025.2515411
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00