A Case of Jaundice Revealing a Hidden Duo: Lemmel’s Syndrome and a Duplicated Gallbladder

Gallbladder duplication is a rare congenital anomaly, often discovered incidentally. Its association with other biliary pathologies, such as choledocholithiasis and Lemmel's syndrome (obstructive jaundice due to periampullary duodenal diverticulum), is uncommon. This case highlights the diagnostic and therapeutic challenges in managing such a complex presentation. A 62-year-old woman, presenting with fever, right upper quadrant pain, and deranged liver function tests, unveiled a diagnostic enigma. Initial ultrasonography suggested the presence of choledocholithiasis, though this finding was later re-evaluated. Subsequent magnetic resonance cholangiopancreatography (MRCP) identified a duplicated gallbladder, with one lobe showing signs of calculous cholecystitis, as well as an 8 mm dilation of the common bile duct (CBD) with a possible filling defect. Adding to the complexity, a large duodenal diverticulum was also identified in the MRCP. Side-viewing duodenoscopy revealed a type II major duodenal papilla. Although initial imaging suggested a filling defect in the CBD, endoscopic retrograde cholangiopancreatography (ERCP) found no stones, and the cause of the biliary obstruction remained unclear. The patient underwent laparoscopic cholecystectomy. The surgical specimen confirmed a rare duplication of the gallbladder with multiple pigment stones in one lobe and chronic cholecystitis. The dilated CBD and obstructive jaundice were attributed to Lemmel's syndrome. This case demonstrates the rare coexistence of a gallbladder duplication and Lemmel's syndrome. Preoperative imaging is crucial for accurate diagnosis and surgical planning in patients with gallbladder anomalies. ERCP plays a vital role in both the diagnosis and treatment of Lemmel's syndrome. This case emphasizes the importance of considering rare anatomical variations and their potential impact on clinical presentation and management.

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Publication Details

Journal
Cureus
Published
2025-06-11
DOI
https://doi.org/10.7759/cureus.85766
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
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article

A Case of Jaundice Revealing a Hidden Duo: Lemmel’s Syndrome and a Duplicated Gallbladder

G.N. Devamsh, Aditya Manjunath, M Saishyam, Nirmal Kumar M
Cureus
Pediatric Hepatobiliary Diseases and Treatments
article

A Case of Jaundice Revealing a Hidden Duo: Lemmel’s Syndrome and a Duplicated Gallbladder

G.N. Devamsh, Aditya Manjunath, M Saishyam, Nirmal Kumar M
article en

Abstract

Gallbladder duplication is a rare congenital anomaly, often discovered incidentally. Its association with other biliary pathologies, such as choledocholithiasis and Lemmel's syndrome (obstructive jaundice due to periampullary duodenal diverticulum), is uncommon. This case highlights the diagnostic and therapeutic challenges in managing such a complex presentation. A 62-year-old woman, presenting with fever, right upper quadrant pain, and deranged liver function tests, unveiled a diagnostic enigma. Initial ultrasonography suggested the presence of choledocholithiasis, though this finding was later re-evaluated. Subsequent magnetic resonance cholangiopancreatography (MRCP) identified a duplicated gallbladder, with one lobe showing signs of calculous cholecystitis, as well as an 8 mm dilation of the common bile duct (CBD) with a possible filling defect. Adding to the complexity, a large duodenal diverticulum was also identified in the MRCP. Side-viewing duodenoscopy revealed a type II major duodenal papilla. Although initial imaging suggested a filling defect in the CBD, endoscopic retrograde cholangiopancreatography (ERCP) found no stones, and the cause of the biliary obstruction remained unclear. The patient underwent laparoscopic cholecystectomy. The surgical specimen confirmed a rare duplication of the gallbladder with multiple pigment stones in one lobe and chronic cholecystitis. The dilated CBD and obstructive jaundice were attributed to Lemmel's syndrome. This case demonstrates the rare coexistence of a gallbladder duplication and Lemmel's syndrome. Preoperative imaging is crucial for accurate diagnosis and surgical planning in patients with gallbladder anomalies. ERCP plays a vital role in both the diagnosis and treatment of Lemmel's syndrome. This case emphasizes the importance of considering rare anatomical variations and their potential impact on clinical presentation and management.

CureusVol. 17(6)
Indra (Spain) (ES), Bangalore Diabetes Centre (IN)
Gender equality
Openalex Percentile: Top 77%
Pediatric Hepatobiliary Diseases and Treatments
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A Case of Jaundice Revealing a Hidden Duo: Lemmel’s Syndrome and a Duplicated Gallbladder — G.N. Devamsh, Aditya Manjunath, et al. · Cureus (2025) | TGRS Research Map | TGRS