Detection of Anti-RuvBL1/2 Autoantibodies by Targeted Liquid Chromatography–Tandem Mass Spectrometry
We propose an immunoprecipitation-based LC-MS/MS MRM method for anti-RuvBL1/2 autoantibody testing. This technology is a promising detection method for autoantibodies targeting conformational epitopes.
Authors
- Carolien Bonroy (ORCID: https://orcid.org/0000-0002-9170-4200)
- Maaike Cockx (ORCID: https://orcid.org/0000-0003-0361-5505)
- Vanessa Smith (ORCID: https://orcid.org/0000-0001-6271-7945)
- Nele Peersman (ORCID: https://orcid.org/0000-0003-0734-313X)
- Tom de Waal (ORCID: https://orcid.org/0000-0001-6863-7903)
- Rita Derua (ORCID: https://orcid.org/0000-0002-1784-0677)
- Jonas De Leeuw
- Ellen De Langhe
- Pieter Vermeersch (ORCID: https://orcid.org/0000-0001-7076-061X)
- Doreen Dillaerts
- Jean‐Baptiste Vulsteke (ORCID: https://orcid.org/0000-0001-5753-2794)
- Yves Piette
- Tom Dehaemers (ORCID: https://orcid.org/0000-0003-4572-9383)
- Takashi Matsushita (ORCID: https://orcid.org/0000-0002-1617-086X)
- Birthe Michiels (ORCID: https://orcid.org/0000-0002-3977-4172)
Institutions
- Kanazawa University (JP)
- Ghent University Hospital (BE)
- Ghent University (BE)
- VIB-UGent Center for Inflammation Research (BE)
- KU Leuven (BE)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1093/jalm/jfaf072
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00