Metrics Selection and Risk Adjustment Methods to Benchmark Inpatient Antibiotic Use
In this cohort study of the nationwide VHA system, there were substantial differences in risk-adjusted benchmarking results between models with only hospital- and unit-level factors and models with hospital-, unit-, and patient-level factors. Future studies should evaluate whether these models with higher content validity also have better construct validity and can inform hospitals and stewardship programs about their objective performance compared with other programs.
Authors
- BRUCE K. ALEXANDER (ORCID: https://orcid.org/0000-0002-4090-2274)
- Michihiko Goto (ORCID: https://orcid.org/0000-0001-6612-5613)
- James A. Merchant (ORCID: https://orcid.org/0000-0001-8709-7914)
- Thomas C. Hanks (ORCID: https://orcid.org/0000-0003-0928-0056)
- Christopher T. Richards (ORCID: https://orcid.org/0000-0003-3728-3860)
- Daniel J. Livorsi (ORCID: https://orcid.org/0000-0001-8523-214X)
- Alexandre Rodrigues Marra (ORCID: https://orcid.org/0000-0002-7577-7688)
- Hyunkeun Cho (ORCID: https://orcid.org/0000-0002-6735-2487)
- Brice Beck
- Matthew Bidwell Goetz (ORCID: https://orcid.org/0000-0003-4542-992X)
- Eli N. Perencevich (ORCID: https://orcid.org/0000-0002-3721-3355)
- David Manuel Hernández
Institutions
- University of Iowa (US)
- University of California, Los Angeles (US)
- Hospital Israelita Albert Einstein (BR)
- University of California San Diego (US)
- Iowa City VA Health Care System (US)
- VA Greater Los Angeles Healthcare System (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.14989
- Citations
- 2
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 2.52
Funders
- U.S. Department of Veterans Affairs
- Office of Research and Development
- Centers for Disease Control and Prevention
- Agency for Healthcare Research and Quality