Sesquiterpenoids from the <i>Homalomena occulta</i> (Lour.) Schott and their anti-osteoclast genesis activity
Seventeen sesquiterpenoids were isolated from the aerial part of <i>Homalomena occulta</i> (Lour.) Schott. Two new compounds, Homoccusions A (<b>1</b>) and B (<b>2</b>), were determined by extensive spectroscopic methods, ECD calculations, as well as MS analysis. Then, the anti-osteoclast genesis effects of all compounds were studied and compounds <b>1-5</b> showed strong inhibition with an osteoclast genesis inhibitory ratio of over 90% at 10 μM.
Authors
- Sicong Jiang (ORCID: https://orcid.org/0000-0002-3032-807X)
- Tao Tang (ORCID: https://orcid.org/0000-0002-8556-394X)
- Cheng Jiang (ORCID: https://orcid.org/0000-0002-5324-7184)
- Bin Zhao
- Yi Wu (ORCID: https://orcid.org/0000-0002-6798-9939)
- Yuping Jiang (ORCID: https://orcid.org/0000-0003-2538-973X)
Institutions
- Jiujiang University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1080/14786419.2025.2512565
- Primary Topic
- Plant Toxicity and Pharmacological Properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00