Evaluation of Immunogenicity of an Orf Virus Vector-Based Vaccine Delivery Platform in Sheep
Both live and inactivated vaccines have the potential to be a platform technology for deployment in sheep. This addresses a notable gap in veterinary vaccine development where the induction of both humoral responses and cellular responses is required without using an adjuvant. The successful use of the MOMP candidate antigen suggests potential utility for bacterial disease deployment.
Authors
- Karen Snedden
- Holly Hill (ORCID: https://orcid.org/0000-0002-8769-5831)
- Colin J. McInnes (ORCID: https://orcid.org/0000-0002-1465-9901)
- Gary Entrican (ORCID: https://orcid.org/0000-0002-8822-2331)
- David J. Griffiths (ORCID: https://orcid.org/0000-0001-9160-0770)
- Rebecca McLean (ORCID: https://orcid.org/0000-0002-4688-3019)
- David Longbottom (ORCID: https://orcid.org/0000-0003-0086-8443)
- Sean Wattegedera (ORCID: https://orcid.org/0000-0002-2218-5144)
- Javier Palarea‐Albaladejo (ORCID: https://orcid.org/0000-0003-0162-669X)
- Lesley Coulter
- Ann R. Wood
- Jackie Thomson
- Ann Percival
- Cameron Cunnea
Institutions
- Biomathematics and Statistics Scotland (GB)
- Moredun Research Institute (GB)
Publication Details
- Journal
- Vaccines
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3390/vaccines13060631
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Rural and Environment Science and Analytical Services Division
- Home Office