Angiotensin Converting Enzyme (ACE) Gene and Muscle Performance in Muay Thai

At present, Martial art sports are very popular. The muscle strength and muscle power are an important factor to contribute the athlete’s performance. It is known that factors that promote physical performances are training, age, sex and genetic differences. Angiotensin converting enzymes (ACE) is the main enzyme in renin angiotensin aldosterone system (RAAS), regulating the circulatory system and water and salts balance in the body. The purpose of this study was to explore the relation between ACE polymorphism and muscle performance in Muay Thai/Thai boxers. The participants were 20 men Thai boxers and 20 controls. The protocols were measure the basic characteristics: weight, height. DNA were extract from buccal cell from mouth-wash method. The polymorphism is a variation of the sequence in the single-nucleotide polymorphisms (SNPs) of ACE gene (insertion or I allele and deletion or D allele) resulting in 3 genotypes: ID, II and DD. The result was showed that the ACE polymorphism ID genotype was highly presented with 55.00% of MuayThai while II and DD genotype was revealed in 45.00% and 25.00% of control groups, respectively. The II genotype in MuayThai showed the significantly different (p £ 0.05) of counter movement jump to ID genotype (50.70 and 46.97, respectively). In contrast with control group that DD genotype presented the highly of CMJ followed by ID and II respectively. This result can be concluded that I allele of ACE genes polymorphism is highly percentage in MuayThai and it was correlated with muscle performance.