Tandem reductive alkylation of quinolines to functionalized tetrahydroquinolines enabled by HFIP
Hexafluoroisopropanol (HFIP)-mediated one-pot tandem reduction of quinolines to tetrahydroquinolines followed by reductive alkylation by the aldehyde has been demonstrated through H-bonding network-enabled substrate activation.
Authors
- Animesh Das (ORCID: https://orcid.org/0000-0003-2178-7116)
- Tapashi Das
- Siddhartha Kumar Senapati
Institutions
- Indian Institute of Technology Guwahati (IN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00519a
- Citations
- 1
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 0.79