Global burden of knee osteoarthritis from 1990 to 2021: Trends, inequalities, and projections to 2035
KOA remains a significant public health concern with increasing burden and widening health inequalities. The projected increases highlight the need for targeted interventions, especially in rapidly growing populations. Preventive measures should focus on reducing high BMI, implementing gender-specific treatments, and addressing regional disparities to mitigate the future burden of KOA.
Authors
- Junjie Chen (ORCID: https://orcid.org/0009-0001-5563-1980)
- Sidi Liu (ORCID: https://orcid.org/0000-0003-4000-6098)
- Shuangshuang Shang
- Huanhuan Dai
- Ming Li (ORCID: https://orcid.org/0000-0001-8882-6613)
- Xin Chen (ORCID: https://orcid.org/0000-0002-3685-0854)
- Tianshu Wang (ORCID: https://orcid.org/0000-0002-1177-3901)
- Zhongfu Tang
- Lili Cheng (ORCID: https://orcid.org/0009-0008-0890-625X)
- Chuanying Huang
Institutions
- Hefei Normal University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Bozhou People's Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1371/journal.pone.0320115
- Citations
- 7
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 11.68
Funders
- National Natural Science Foundation of China