Immune response induced by the recombinant novel coronavirus vaccine (Adenovirus type 5 vector) (Ad5-nCoV) in persons living with HIV (PLWH)
The Ad5-nCoV vaccine was safe and induced an adequate immune response in virologically suppressed PLWH, maintaining high antibody titers at least during the first year post-vaccination. No significant changes were observed in plasma viral load, CD4 count and CD4/CD8 ratio.
Authors
- Valeria Fink (ORCID: https://orcid.org/0000-0003-3994-4781)
- Scott A. Halperin (ORCID: https://orcid.org/0000-0003-0525-589X)
- Patricia Patterson
- Jin-Bo Gou
- Pedro Cahn (ORCID: https://orcid.org/0000-0002-9381-1931)
- Gustavo Lopardo (ORCID: https://orcid.org/0000-0002-0886-2380)
- Lucrezia Gambardella (ORCID: https://orcid.org/0000-0003-3899-5958)
- Tao Zhu (ORCID: https://orcid.org/0000-0003-4197-0065)
- Wang RuiJie (ORCID: https://orcid.org/0000-0002-4110-6552)
- A Nava (ORCID: https://orcid.org/0000-0002-5383-1380)
- Isabel Cassetti (ORCID: https://orcid.org/0009-0003-4399-2628)
- Luis Barreto
- Mariela Ceschel
- Gissella Mernies
- María José Rolón
- María Inés Figueroa (ORCID: https://orcid.org/0000-0002-0091-5150)
Institutions
- Dalhousie University (CA)
- Hospital Fernández (AR)
- Fundación Huésped (AR)
- CanSino (China) (CN)
- Helios Salud (AR)
- Fundación Centro de Estudios Infectológicos (AR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1371/journal.pone.0312893
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00