Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 ameliorate barrier dysfunction in human induced pluripotent stem cell-derived crypt-villus structural small intestine
The results indicate that LAB ameliorate the cytokine-induced dysfunction of intestinal barrier integrity and homeostasis disrupted by cytokines in a co-culture model of hiPSC-SI and LAB.
Authors
- I. Ogawa (ORCID: https://orcid.org/0000-0002-5021-1717)
- K. KOBAYASHI
- Yukio Kaneda (ORCID: https://orcid.org/0000-0001-7963-0985)
- Takahiro Iwao (ORCID: https://orcid.org/0000-0002-2452-9043)
- Tamihide Matsunaga (ORCID: https://orcid.org/0000-0002-2083-1974)
- Junko Mochizuki
- Yuri Mizuno
- Toshihiro Sashihara (ORCID: https://orcid.org/0000-0001-7617-0987)
- Fuka Yamazaki (ORCID: https://orcid.org/0009-0000-5731-0614)
- Takaaki Nakai (ORCID: https://orcid.org/0000-0002-4083-6123)
- Yumiko Watanabe‐Yasuoka (ORCID: https://orcid.org/0009-0005-7911-8208)
- Yuka Shimizu
- Yuri Imai
Institutions
- Nagoya City University (JP)
- Middle East Institute of Japan (JP)
- Oji Holdings (Japan) (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1585007
- Citations
- 1
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Japan Society for the Promotion of Science