Multimodal Management of Refractory Ventricular Tachycardia Due to Aconitine Poisoning: A Case Report in a Resource-Limited Setting

Aconitine, a potent plant alkaloid used in traditional Asian medicine, possesses significant toxicity risks. This case report presents a 42-year-old male with alcohol use disorder who developed life-threatening ventricular tachycardia after ingesting a homemade herbal liqueur. Initially thought to contain <i>Cassia alata</i> (candle bush), further investigation revealed that the tincture was instead prepared from <i>Aconitum</i> root (Wolfsbane) based on advice from an online social media video. He subsequently developed life-threatening ventricular tachycardia and cardiac arrest refractory to initial interventions. In the absence of extracorporeal membrane oxygenation (ECMO), flecainide, or procainamide, a multimodal approach involving multiple antiarrhythmics, including amiodarone, phenytoin, and stellate ganglion block, ultimately restored normal sinus rhythm. This case underscores the importance of early recognition and a flexible, multimodal treatment strategy in managing aconitine-induced arrhythmias, especially in resource-limited settings.

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Publication Details

Journal
Journal of the American College of Emergency Physicians Open
Published
2025-06-11
DOI
https://doi.org/10.1016/j.acepjo.2025.100171
Citations
1
Primary Topic
Plant-based Medicinal Research
Type
article
Field-Weighted Citation Impact
1.56
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article

Multimodal Management of Refractory Ventricular Tachycardia Due to Aconitine Poisoning: A Case Report in a Resource-Limited Setting

Patipan Sitthiprawiat, Pavita Laohakul, Borwon Wittayachamnankul
1 citations
Journal of the American College of Emergency Physicians Open
Plant-based Medicinal Research
1.56
article

Multimodal Management of Refractory Ventricular Tachycardia Due to Aconitine Poisoning: A Case Report in a Resource-Limited Setting

Patipan Sitthiprawiat, Pavita Laohakul, Borwon Wittayachamnankul
article en
1 citations

Abstract

Aconitine, a potent plant alkaloid used in traditional Asian medicine, possesses significant toxicity risks. This case report presents a 42-year-old male with alcohol use disorder who developed life-threatening ventricular tachycardia after ingesting a homemade herbal liqueur. Initially thought to contain <i>Cassia alata</i> (candle bush), further investigation revealed that the tincture was instead prepared from <i>Aconitum</i> root (Wolfsbane) based on advice from an online social media video. He subsequently developed life-threatening ventricular tachycardia and cardiac arrest refractory to initial interventions. In the absence of extracorporeal membrane oxygenation (ECMO), flecainide, or procainamide, a multimodal approach involving multiple antiarrhythmics, including amiodarone, phenytoin, and stellate ganglion block, ultimately restored normal sinus rhythm. This case underscores the importance of early recognition and a flexible, multimodal treatment strategy in managing aconitine-induced arrhythmias, especially in resource-limited settings.

Journal of the American College of Emergency Physicians OpenVol. 6(4)
Chiang Mai University (TH)
Zero hunger
Openalex Percentile: Top 19%
Plant-based Medicinal Research
1.56
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