Multimodal Management of Refractory Ventricular Tachycardia Due to Aconitine Poisoning: A Case Report in a Resource-Limited Setting
Aconitine, a potent plant alkaloid used in traditional Asian medicine, possesses significant toxicity risks. This case report presents a 42-year-old male with alcohol use disorder who developed life-threatening ventricular tachycardia after ingesting a homemade herbal liqueur. Initially thought to contain <i>Cassia alata</i> (candle bush), further investigation revealed that the tincture was instead prepared from <i>Aconitum</i> root (Wolfsbane) based on advice from an online social media video. He subsequently developed life-threatening ventricular tachycardia and cardiac arrest refractory to initial interventions. In the absence of extracorporeal membrane oxygenation (ECMO), flecainide, or procainamide, a multimodal approach involving multiple antiarrhythmics, including amiodarone, phenytoin, and stellate ganglion block, ultimately restored normal sinus rhythm. This case underscores the importance of early recognition and a flexible, multimodal treatment strategy in managing aconitine-induced arrhythmias, especially in resource-limited settings.
Authors
- Patipan Sitthiprawiat
- Pavita Laohakul (ORCID: https://orcid.org/0000-0002-9925-3301)
- Borwon Wittayachamnankul (ORCID: https://orcid.org/0000-0003-3465-5534)
Institutions
- Chiang Mai University (TH)
Publication Details
- Journal
- Journal of the American College of Emergency Physicians Open
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1016/j.acepjo.2025.100171
- Citations
- 1
- Primary Topic
- Plant-based Medicinal Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56