Development and validation of a multienzyme isothermal rapid amplification and lateral flow dipstick combination assay for HTLV-1 proviral DNA detection
This study established a method based on MIRA-LFD for detecting HTLV-1 proviral DNA, which has the advantages of fast, accurate, good sensitivity, strong specificity, simplicity, and portability. This method meet the needs of rapid on-site detection and is easy to promote and use in grassroots medical institutions or blood stations.
Authors
- Jue Xie (ORCID: https://orcid.org/0000-0002-4270-671X)
- Dawei Cui (ORCID: https://orcid.org/0000-0003-3840-1486)
- Mengjiao Lin (ORCID: https://orcid.org/0000-0002-1462-4098)
- Miaomiao Li (ORCID: https://orcid.org/0000-0002-7328-0205)
- Yushan Xu
Institutions
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1186/s12967-025-06642-9
- Citations
- 2
- Primary Topic
- T-cell and Retrovirus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province