Tissue-specific transcriptomic adaptation in three strains of chickens during coinfections with parasites

In general, slower-performing strains effectively initiated responses favouring worm expulsion and tissue repair in the jejunum, whereas high-performing strains predominantly showed inflammatory responses in the caecum and liver. These findings highlight tissue-specific adaptations underlying strain-dependent tolerance to coinfections with mixed parasites.

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Publication Details

Journal
Gut Pathogens
Published
2025-06-11
DOI
https://doi.org/10.1186/s13099-025-00716-1
Primary Topic
Animal Nutrition and Physiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Tissue-specific transcriptomic adaptation in three strains of chickens during coinfections with parasites

Cornelia C. Metges, Henry Reyer, Solvig Görs, Nares Trakooljul et al.
Gut Pathogens
Animal Nutrition and Physiology
article

Tissue-specific transcriptomic adaptation in three strains of chickens during coinfections with parasites

Cornelia C. Metges, Henry Reyer, Solvig Görs, Nares Trakooljul, Gürbüz Daş, Oyekunle John Oladosu
article en

Abstract

In general, slower-performing strains effectively initiated responses favouring worm expulsion and tissue repair in the jejunum, whereas high-performing strains predominantly showed inflammatory responses in the caecum and liver. These findings highlight tissue-specific adaptations underlying strain-dependent tolerance to coinfections with mixed parasites.

Gut PathogensVol. 17(1)
Research Institute for Farm Animal Biology (FBN) (DE)
European Commission
Openalex Percentile: Top 85%
Animal Nutrition and Physiology
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