Ferroximend Improves Nonvascularized Bone Graft Incorporation in the Irradiated Rat Mandible
Our results suggest that the implantation of Ferroximend during NVBG reconstruction can remediate the damaging effects of radiotherapy. Upon clinical translation, countless patients may benefit from the successful reintroduction of nonvascularized bone grafting as a reconstructive option in oncologic reconstruction after radiotherapy.
Authors
- Laird Forrest
- Emma Wessels
- Jeremy V. Lynn (ORCID: https://orcid.org/0000-0001-7107-3635)
- Kevin M. Urlaub
- Steven R. Buchman (ORCID: https://orcid.org/0000-0001-9742-558X)
- Alexis Donneys (ORCID: https://orcid.org/0000-0001-8690-0971)
- Keshav B. Lalchandani
- Mark S. Cohen (ORCID: https://orcid.org/0000-0002-2517-0757)
- Noah S. Nelson
- Melissa Daniel
- Kyle Cragg
- Navya Singh
Institutions
- University of Kansas (US)
- University of Michigan (US)
- Orthopaedic Research Laboratories (US)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1097/sap.0000000000004355
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00